Effects of controlled low central venous pressure combined with dexmedetomidine on the blood loss, renal function and cognitive function in patients undergoing laparoscopic hepatectomy

This study aims to investigate the effects of controlled low central venous pressure combined with dexmedetomidine on blood loss, renal function and cognitive in patients undergoing laparoscopic hepatectomy. From January 2021 October 2022, 90 treated hepatectomy Huai’an First People’s Hospital were selected as subject objects equally divided into group control a random method. The surgical duration, duration hepatic portal occlusion, serum bilirubin, creatinine, urea nitrogen, hemoglobin, plasma albumin, interleukin (IL)-6 two groups compared. Patients receiving combination showed less loss shorter time occlusion compared group. levels creatinine nitrogen significantly increased at postoperative 3 days preoperation groups. In particular, these factors higher than that days, indicating better liver those hemoglobin albumin observed after surgery At 1 day surgery, level IL-6 was lower achieved mini-mental state examination (MMES) scores day, 7 days. is promising clinical practice decreasing improving kidney function, protecting during